Regulation of obesity and insulin resistance by hypoxia-inducible factors
نویسندگان
چکیده
منابع مشابه
Regulation of obesity and insulin resistance by hypoxia-inducible factors
In obesity, dysregulated metabolism and aberrant expansion of adipose tissue lead to the development of tissue hypoxia that plays an important role in contributing to obesity-associated metabolic disorders. Recent studies utilizing adipocyte-specific hypoxia-inducible factor-α (HIF-α) gain- or loss-of-function animal models highlight the pivotal involvement of hypoxic responses in the pathogene...
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ژورنال
عنوان ژورنال: Hypoxia
سال: 2014
ISSN: 2324-1128
DOI: 10.2147/hp.s68771